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Unlike topical selftanners that merely stain the outer layer of skin, this agent drives an internal biological response, closer in spirit to what happens after UV exposurejust via a drug-like mechanism rather than sunlight
It is administered subcutaneously in the abdomen, thigh, or upper arm at 0.6 mg daily, increasing weekly until reaching 3 mg
In a Novo Nordisk funded study of 3,417 adults without diabetes and with a BMI of 30 or higher, or a BMI of 27 or higher with at least one obesity-related complication, participants achieved an average 20.4% weight loss with cagrilintidesemaglutide, compared with 3.0% with placebo 14
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