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In the SURMOUNT-1 trial, tirzepatide produced dose-dependent weight reductions, with average losses approaching or exceeding ~20% at higher doses in adults with obesity who did not have diabetes, numbers that markedly exceed historical pharmacotherapy benchmarks

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While both belong to the GLP-1 receptor agonist class, their FDA approvals, dosing schedules, and intended uses vary significantly

At the same time, unresolved questions aren't something you should wave away

CoQ10 in older mothers , some clinicians continue a low-to-moderate dose through early pregnancy if you're over 38, though this is not a formal guideline recommendation