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non-recurrence, n = 8)
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Retatrutide targets three hormone receptors (GLP-1, GIP, and glucagon), while Mounjaro (Tirzepatide) activates two (GLP-1 and GIP)
Presented for research literature review only Abdul Karim D (2025)
However, novel dual receptor agonists have been developed for the treatment of obesity and T2D under the concept that GLP-1 restrains the hyperglycemic action of glucagon, while allowing it to exert its beneficial actions on bodyweight, food intake, lipid metabolism and thermogenesis (71)
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