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In clinical trials of GLP-1 medications, adults lost a mean of roughly 15% of body weight over about a year (STEP-1, Novo Nordisk
DOI: 10.1038/s41591-024-03412-w
[3] The British Society for Haematology guidelines emphasise that the response to treatment should be monitored through clinical assessment and blood count testing, rather than routine measurement of B12 levels after treatment has started
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These effects are usually manageable by increasing the dose gradually and staying well hydrated, which is why supervised dosing schedules matter
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