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Advani noted that the cost of the GLP-1 medications, side effects and the potential of having to take them long term are drawbacks

The interesting question is not just: What does each supplement do individually? The better question is: how do NMN, TMG, and GlyNAC complement each other within a modern longevity strategy

Repeated measurement is also advised if chelation therapy fails, to rule out the interim development of CIAIH, which may require treatment with steroids

Emerging research is investigating whether lower maintenance doses might sustain weight loss while reducing cost and side effect burden, but this approach is not yet supported by randomized controlled trials and should only be undertaken with physician guidance

DOI: 10.3389/fcell.2021.646113 [Google Scholar] Andreozzi F, Raciti GA, Nigro C, Mannino GC, Procopio T, Davalli AM, et al