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Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound) in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, as an adjunct to diet and physical activity
Before and After Mounjaro: Improvements Beyond Weight While Mounjaro is not specifically for weight loss treatment , clinical trials confirm that it significantly improves blood sugar levels and overall health outcomes
Its prevalence is increasing worldwide, and, like obesity, it affects progressively younger populations compared to the past, with potentially greater impact on chronic complications
Conversely, normal oxidative-stress biomarkers do not rule out atherosclerosis, high blood pressure, inherited cardiovascular risk, structural heart disease, or other health concerns
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