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Use raw heart-rate change rather than placebo-subtracted when assessing drug-attributable load: the placebo arm shows real cardiovascular adaptation from weight loss and lifestyle counseling, so subtraction over-corrects
This includes patients with acute muscle strains, tendon irritation, ligament sprains, plantar fascia irritation, Achilles tendinopathy, patellar tendinopathy, rotator cuff irritation, tennis elbow, golfers elbow, or localized joint-adjacent soft-tissue pain
Many patients notice improved energy levels and reduced fatigue within 12 weeks of starting intramuscular B12 injections
The placement of the subcutaneous catheters and handling of the infusion pump were readily accomplished and well accepted by the patients and their families
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