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Monitor for severe nausea, vomiting, or diarrhea , and seek medical attention if symptoms are severe

Seek same-day medical assessment if you develop: Joint pain with fever and systemic symptoms to exclude septic arthritis, which requires urgent treatment Inability to bear weight or severe functional impairment Contact your GP within 24-48 hours if you develop: New joint pain and swelling that could represent gout Recurrent gout attacks despite previous management Multiple joints affected simultaneously this may suggest alternative diagnoses Inability to bear weight or perform normal activities due to joint pain If you cannot access your GP and symptoms are severe, contact NHS 111 or attend an urgent care centre for advice

Lack of Long-Term Data: While Semaglutide shows promise, more long-term studies are needed to fully understand its effects on kidney health, especially in individuals with advanced kidney disease

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Glucagon-like peptide-1 receptor agonists and the appropriate measurement of gastric emptying