Pancreatic enzyme 4X (Protease, Amylase, Lipase), Bromelain (from Pineapple)
It first drew research interest for its ability to heal stomach ulcers and inflammatory bowel conditions, then expanded to tendon, ligament, muscle, and even bone healing across dozens of preclinical studies (Sikiric et al., PubMed)
2026 Mar 12;19(3):463
Reduces Dark Spots and Hyperpigmentation: Effectively brightens blemishes, sun spots, and uneven skin patches for a smooth complexion
doi: 10.3389/fnmol.2021.750726 Received 31 July 2021 Accepted 26 November 2021 Published 23 December 2021 Volume 14 - 2021 Edited by Yi Yang, The First Hospital of Jilin University, China Reviewed by Wei Chen, Gan & Lee Pharmaceuticals, China