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The hypoglycemic strategy has also shifted from sugar control to both sugar control and heart protection

Yang H, Kuhn C, Kolben T, et al

There is a theoretical case for using both in certain patients, targeting different physiological mechanisms simultaneously, though this approach is under evaluation and not yet standard of care

Given its high usage and availability as an over-the-counter analgesic, a systematic review of paracetamols efficacy and tolerability in individual conditions is warranted (Roberts et al., 2016)