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Additionally, ISF increased expressions of lipid metabolism-related genes in epididymal WAT: peroxisome proliferator-activated receptor (Ppar ), adipose triglyceride lipase (Atgl), and hormone-sensitive lipase (Hsl) ( Supplementary Figures 2AC ), while protein expression level of uncoupling protein-1 (UCP-1) in I-BAT was unaltered ( Supplementary Figures 2D, E )

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The injection is typically done at home, and many patients find the weekly administration less burdensome than daily pill-taking

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This is an important distinction that often causes confusion