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The dosing protocol matters because titrating too fast is the main cause of intolerable side effects

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Oral hygiene measures can be particularly effective: Brush teeth and tongue thoroughly at least twice daily using a fluoride toothpaste Use an alcohol-free mouthwash or a bicarbonate of soda rinse to neutralise taste Maintain regular dental check-ups to exclude oral health issues Stay well-hydrated throughout the day to prevent dry mouth Chew sugar-free gum or suck sugar-free mints to stimulate saliva production Dietary adjustments may also help

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Cardiac lipotoxicity: molecular pathways and therapeutic implications