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Nutritional influences on brain function Nutrients (2024)
A popular dual agonist, tirzepatide (Mounjaro), activates both GLP-1R and GIPR, producing synergistic effects on insulin secretion, appetite suppression, and weight reduction (Table 1)
Together, these compounds form a complementary group of molecular tools used to investigate incretin biology, receptor pharmacology, and integrated metabolic signaling networks in controlled biochemical assays, cell culture systems, and metabolic animal models
doi:10.1016/j.biochi.2016.02.012 [PubMed] [Elsevier] Moll S, Varga EA
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