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Why Vitamin B12 Matters for Nerve Health Vitamin B12 (cobalamin) is an essential water-soluble vitamin required for: Myelin repair (protective coating around nerves) Neurotransmitter function DNA synthesis & cellular repair Red blood cell formation & oxygen delivery The body cannot manufacture B12 , and deficiency is common especially among older adults, vegans/vegetarians, people with absorption disorders, and those taking drugs like metformin
However, two practical interactions are worth noting for research protocols
Long-term effects in humans are unknown
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2008 May 15;453(7193):314-21
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