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For semaglutide, such concerns have been addressed in the extensive phase 3 registration trials including cardiovascular outcome trials for both subcutaneous (SUSTAIN: Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) and oral (PIONEER: Peptide InnOvatioN for the Early diabEtes tReatment) semaglutide and are being studied in further trials and registries, including real world data studies
& Shen, J
Attenuated desensitization of -adrenergic receptor by water-soluble N-nitrosamines that induce S-nitrosylation without NO release
Systemic inflammatory regulators and risk of acute-on-chronic liver failure: a bidirectional mendelian-randomization study
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