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After birth, the lambs exhibited metabolic acidosis, a blood disorder involving changes such as decreased blood pH, lower total carbon dioxide, bicarbonate, and ionized calcium levels, and base excess, as well as increased lactate concentrations ( + -like currents mediated by the 5-hydroxytryptamine 1A receptor, leading to reduced intrinsic excitability and slower tuberoinfundibular dopamine (TIDA) network rhythms, thereby increasing prolactin secretion
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As such they are a vital mechanism to address inequities in the social determinants of health in the US
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