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The pooled estimates may be underestimates of the efficacy of newer agents, although the review could not determine whether stronger weight-loss effects necessarily translate into greater reductions in binge eating

Potential Risks for Long-Term or Frequent Use If you find yourself needing pain relief frequently, it is important to consider the potential long-term risks of combining these medications

A provider might prescribe both if a patient has reached a weight loss plateau on one medication

Chemical and histochemical studies of normal and diseased human gastrointestinal tract: A comparison between histologically normal colon, colonic tumors, ulcerative colitis and diverticular disease of the colon

mBio 9 (3), 112