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AOD-9604, despite a safety database spanning six trials and around 900 participants, saw its early positive efficacy signal fail to replicate in its largest confirmatory trial meaning its safety data is well established

Research indexed on PubMed suggests DSIP has been studied in animal models in the contexts of response to stress, hormone modulation, and neuroprotection

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For metabolic goals the panel is metabolic: fasting glucose, A1c, lipids, and objective body composition rather than scale weight

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