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2020;367(6478):eaau6977
Animal studies indicate a plasma half-life of approximately 1-2 hours, with rapid tissue distribution facilitating its role in wound contraction and epithelialization
GSH and oxidative stress Most GSH is utilized in antioxidant defense in cells by three members of the glutathione peroxidase (GPx) enzyme family and by one of the peroxiredoxins (Prdx 6)
Elevation of homocysteine arises from reduced activity of methionine synthase, a vitamin B 12 -dependent enzyme, however, this does not increase GSH biosynthesis
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