The American Academy of Family Physicians and NIH identify the following clinical manifestations: Fatigue and generalized weakness Megaloblastic anemia (abnormally large, immature red blood cells) Tingling or numbness in the hands and feet (peripheral neuropathy) Difficulty walking and balance problems Cognitive disturbances including memory difficulty and confusion Mood changes, including depression and irritability Glossitis (swollen, inflamed tongue) Early symptoms such as fatigue and mild tingling are often attributed to stress, aging, or other conditions
Alzheimer Res ., 16 , 622632
Your psychiatrist, for example, may be able to switch you from paroxetine (weight-promoting) to sertraline (weight-neutral) with the same therapeutic benefit
As noted by Kraus et al., Nature Medicine , NNMT inhibition in white adipose tissue significantly increased energy expenditure and reduced fat mass in animal models without changes to diet or activity
Very happy my energy level is back I feel alive Theyve really helped curb my appetite and Im sleeping so much better