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The two pathways converge on GH release but through different intracellular cascades, which is why combining a GHS-R1a agonist (like ipamorelin) with a GHRH analog (like CJC-1295) produces a synergistic rather than merely additive GH response
Pooyandjoo M, Nouhi M, Shab-Bidar S, Djafarian K, Olyaeemanesh A
CLINICAL RELEVANCE Evidence that glutathione is involved in the metabolic disturbances which underlie diabetes, obesity, insulin resistance, and the metabolic syndrome continues to grow as well
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