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Liraglutide and semaglutide for type 2 diabetes Ozempic, Rybelsus (semaglutide) and Victoza (liraglutide) are indicated for managing type 2 diabetes

The introduction of this new indication may have led to a broader user population, consequently resulting in a higher number of reported adverse reactions

The clinical relevance of gastrointestinal adverse events associated with GLP-1 RAs depends not only on their incidence but also on their severity, duration, and impact on patient quality of life

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation