In human cell culture studies, increased expressions of PAI-1 and VCAM-1 have been reported to be associated with hyperglycemia-related endothelial cell dysfunction, a process that predisposes vasculature to accelerated atherogenesis 52
Wegovy also has been approved as a treatment to reduce the risk of heart attack and stroke
doi: 10.1093/sxmrev/qead055
Saunders, MD, DABOM, the founder and executive vice president at Intellihealth, agrees, pointing out that weight regain, as well as an increase in hunger, cravings, [and] food noise, may cause some patients to feel anxious or depressed. However, others may report the opposite
Adv Wound Care 7:209231 Lee J, Rodero MP, Patel J, Moi D, Mazzieri R, Khosrotehrani K (2018) Interleukin-23 regulates interleukin-17 expression in wounds, and its inhibition accelerates diabetic wound healing through the alteration of macrophage polarization