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Understanding GLP-1 Medications and Their Role Glucagon-like peptide-1 (GLP-1) receptor agonists mimic a natural hormone released after eating
In this work we directly compare the prototypical GLP-1RA exendin-4 with its C-terminally acylated analogue, exendin-4-C16, for their relative propensities to recruit and activate G proteins and -arrestins, endocytic and post-endocytic trafficking profiles, and interactions with model and cellular membranes
However, the dosage may vary according to individual needs
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