GLP-1 induces the ileal brake phenomenon by inhibition of gastric emptying and intestinal transit time
(This relieves the kidneys and the rest of the body from the strain of forcing a higher dose on it over a shorter period of time)
News Release February 24, 2022 Consumers Returned to Pre-Pandemic Supplement Usage in 2021, ConsumerLab Survey Reveals White Plains, New York, February 24, 2022 A survey of 8,049 people who use dietary supplements shows many supplements that declined in use in 2020 began bouncing back in 2021, such as magnesium (+2.4 percentage points), and CoQ10 (+2.7 pts)
For this, a device most commonly called a dermapen is used
Armstrong MJ, Gaunt P, Aithal GP, et al