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Ghrelin acts on reward-related pathways by stimulating dopamine neurons in the ventral tegmental area and promoting dopamine turnover in the nucleus accumbens, a region of the ventral striatum ( Preclinical models indicate that the GLP-1 R system has evolved, at least in part, to regulate feeding-related motivation ( Repeated dosing is probably crucial for positive effects in depression and suicidality
If you are using the supplement during recovery from illness, periods of poor appetite, or increased nutritional requirements, continue taking it for the full duration recommended by your doctor, even if you start feeling better earlier
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The results become murky, inconsistent, and ultimately, unreliable
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