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Lithium remains the first-line therapy for manic-depressive illness, bipolar disorder 14 , traumatic brain injury 15 , and numerous neurodegenerative diseases, such as Alzheimers, Huntingtons, and Parkinsons diseases 16

We further thank the UK Biobank Resource, with the replication analysis in this study having been conducted under application number 95801

Once inflammation and oxidative stress start building up and superseding the amount of available antioxidants like glutathione, they can cause damage to cells and the mitochondria inside of cells leading to memory loss, anxiety, depression, joint pain, fatigue, weakness, weight gain, and increased risk of diabetes, heart disease, and cancer

Exposure to these chemicals might elevate the risk of metabolic disorders, developmental and reproductive defects, and endocrine-related cancers

In the case of naltrexone-bupropion, bupropion is known for its use as a single agent for depression and for smoking cessation and has been found to promote weight loss at 300 or 400 mg daily