Respuesta Rpida: La semaglutida acta como un anlogo del GLP-1 que estimula la secrecin de insulina dependiente de glucosa, suprime el glucagn, retrasa el vaciamiento gstrico y reduce el apetito mediante receptores en pncreas, cerebro y tracto gastrointestinal
This trial enrolled patients (n = 338) who were newly diagnosed with diabetes, patients treated only with diet and exercise, patients treated with a single antidiabetic medication (sulfonylureas, alpha-glucosidase inhibitors, thiazolidinediones, or meglitinides), and patients (n = 368) receiving metformin HCl up to 1500 mg/day plus a sulfonylurea at a dose equal to or less than one-half the maximum dose
Physiol Rev (2019) 99(3):1381431
The stria vascularis maintains the high positive Organ of Corti Endolymphatic Potential (EP)
Origlia and colleagues further demonstrated L-PC-associated reduction in lipid hydroperoxide content and morphological abnormalities associated with chronic CyA administration [57]