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5.4 Adjunctive therapies used in IBD treatment (prebiotics, probiotics, and postbiotics) Adjunctive therapies such as prebiotics, probiotics, and postbiotics are used in managing oxidative stress and the treatment of IBS and IBD, as presented in Table 4

While these can reduce inflammation, they often bring difficult side effects: Weight gain, bloating, and bone loss Increased infection risk Fatigue and mood changes High long-term costs Because these drugs suppress the immune system instead of balancing it, flare-ups frequently return once treatment stops

mSphere 1 , e0018716 (2016)