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Br J Clin Pharmacol 40:431438 Fisher NDL, Danser AHJ, Nussberger J, Dole WP, Hollenberg NK (2008) Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans
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The mechanism for IFN-- and IL-17-associated disease pathogenesis includes their downstream effector chemokines, such as IFN--inducible protein of 10 kDa (IP-10 or CXCL10) and monokine-induced by IFN- (MIG or CXCL9) that upregulate matrix metalloproteinases (MMP)12 and MMP9 69