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While the Both diabetes and vitamin B12 deficiency can independently lead to neuropathy

Adverse reactions: mild transient diarrhea, polycythemia vera, peripheral vascular thrombosis, transient rash itching, bloating sensation

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Nanogels are hydrogelbased nanoparticles with a threedimensional crosslinked polymer network that encapsulate small molecules, proteins, nucleic acids and live microorganisms, offering high water content, biocompatibility and responsiveness to stimuli (pH, temperature, enzymes) that provide protection and controlled release for both drugs and probiotics [141]