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Peter Attia 18 Feb 23 Lean mass loss on GLP-1 receptor agonists: a downside of the miracle drugs Clinical trials have generated impressive data on the effects of GLP-1 agonists on body weight and BMI, but how do these drugs perform in terms of body composition
Some users described: improved calmness reduced stress reactivity improved sleep lower anxiety during recovery better overall well-being following gastrointestinal improvement Others reported: emotional blunting anhedonia altered stimulant response decreased motivation unusual mood flattening Researchers suggest BPC-157 does not boost brain activity like a stimulant
10.1007/s12298-012-0108-8 73 TripathiR
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Together, these pathways help scientists examine metabolic regulation in laboratory models
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