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Some conditions that may be associated with MTHFR gene mutations Autism Addictions: smoking, drugs, alcohol Downs syndrome Frequent miscarriages Male & female infertility Pulmonary embolism and other blood clots Depression & anxiety Schizophrenia Bipolar disorder Fibromyalgia Chronic Fatigue Syndrome Chemical Sensitivity Parkinsons disease Irritable Bowel Syndrome Stroke Spina bifida Migraines Hyperhomocysteinemia Breast cancer Atherosclerosis Alzheimers Multiple Sclerosis Myocardial Infarction (Heart Attack) Methotrexate Toxicity Nitrous Oxide Toxicity Treatment for MTHFR Fortunately, you can easily be tested for the MTHFR mutation

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Several mutations have been identified in the phase I and II detoxification genes required for acetaminophen metabolism, which may affect the rate of acetaminophen clearance or production of the toxic metabolite NAPQI (Zhao 2011)