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Stromal DHAR was thought to be superfluous, given the fast chemical reduction of dehydroascorbate (DHA) by reduced glutathione (GSH), particularly at alkaline pH (Foyer and Halliwell 1976, 1977)

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The original Sikiric 1999 study likewise reported "evident angiogenic property" and stimulation of granulation-tissue formation in rats (Sikiric et al., 1999)

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