Gut health is another area where inflammation plays a significant role
Case example : A patient receives anesthesia for caesarean delivery
found in some OTC cosmetics Off-label use discussed here: wound healing (topical and injectable) Evidence level: preclinical strong, human clinical limited (GRADE equivalent: very low to low) Key mechanism: upregulates collagen I/III, VEGF, decorin, and anti-inflammatory cytokines Typical compounded concentration: 0.01% to 1% topical
Collectively, these mechanistic insights demonstrate the multifaceted role of gut dysbiosis in shaping brain behaviour and highlight the therapeutic potential of microbiome-targeted interventions, such as probiotics and faecal microbiota transplantation (FMT), in mitigating neuropsychiatric and neurodegenerative conditions
Among the various types of stem cell therapies explored, the use of mesenchymal stem cells appears to be the most promising