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At excess doses, this pathway could theoretically increase circulating free fatty acids, but no published human trial has reported clinically significant dyslipidemia from acute AOD-9604 overexposure
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However, none of these studies specifically addressed the impact of such supplementation on PBMC metabolism during an inflammatory challenge
Higher concentrations can actually improve stability in some cases because the peptide molecules essentially buffer each other, but they also create more opportunity for aggregation under heat stress
The issue is often bioavailability, not dosage
