Additional factors warranting consideration include active malignancy, recent surgery or trauma, use of oestrogen-containing contraceptives or hormone replacement therapy, smoking, and certain inflammatory conditions such as inflammatory bowel disease
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Methylation of B3GAT2 (beta-1,3-glucuronyltransferase 2), CCNA1 , TFPI2 , TWIST1 , VIM , and ZNF793 (Zinc finger protein 793) can be confirmed using MethyLight PCR and Cytosponge, a non-endoscopic tool ( TFPI2 has shown promise as a diagnostic biomarker for BE
Pettegrew JW, Levine J, McClure RJ
doi: 10.1016/j.ejpn.2015.09.001 76