Also, this line from their statistical analysis feels like a smoking gun to me that this is more publicity stunt than important science We estimated that a sample size of 700 participants (350 per group) would provide approximately 90% power to s (emphasis mine) how that tirzepatide was superior to semaglutide with respect to the mean percent change in body weight from baseline to week 72
UK patients and clinicians can search for eligible trials via: NIHR Be Part of Research (bepartofresearch.nihr.ac.uk) the primary UK portal for finding clinical trials CTIS Public Portal (euclinicaltrials.eu) the EMA's Clinical Trials Information System, which covers trials in the EU and EEA ClinicalTrials.gov a global registry of clinical studies Patients interested in participating should speak with their GP or specialist, who can advise on eligibility and refer to appropriate trial centres if suitable
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In each figure, week zero represents the percentage difference between a patients average weight from the year prior to starting semaglutide and their weight when starting semaglutide
Oral melanotic macules An oral melanotic macule, by conventional definition is a focal, well-defined, uniformly coloured oral mucosal hyperpigmentation, less than 1 cm in diameter, of unknown aetiology