labial melanotic macule skin cancer freckle on lip This lovely patient was thrilled with her beautiful result after laser treatment of oral macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Melanotic macule. Benign. Dark spot

GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice

It is classified as an essential vitamin but may be better thought of as The Stress Hormone. See the write up on the many vital functions of vitamin C for more details

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The drug can also reduce appetite by slowing the rate at which the stomach empties, and possibly through effects on the brain