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Surgical options (including CSF [cerebrospinal fluid] shunts, venous sinus stenting, optic nerve fenestration, bariatric surgery) carry procedure-related risks and meaningful failure rates

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This could create different product lanes for oral GLP-1s, high-efficacy injectables, amylin combinations, triple agonists, and maintenance therapies

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Conjugation stability ensures safety, while a consistent DAR underpins reproducible pharmacokinetics and efficacy for ADCs