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The rationale was that direct delivery to the joint would maximize local efficacy while minimizing systemic exposure
The articles from Drugs.com, WebMD, MedicineNet, and Biom do not reference any study to back up their claim, whereas the other three articles all cite an experiment performed on brewers yeast called Impact of glutathione metabolism on zinc homeostasis in Saccharomyces cerevisiae
Wang L, Azad N, Kongkaneramit L, Chen F, Lu Y, Jiang BH, Rojanasakul Y (2008) The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation
References 1 AhmedH
Swim latency, swim distance, time spent in the target quadrant, and number of quadrant crossings were recorded using a computerized video tracking system [2]
