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The enzyme glutathione reductase (GR) , utilizing the coenzyme NADPH, steps in to break the disulfide bond, recycling GSSG back into the active, reduced GSH state
In mouse models of AD, GLP-1 receptor agonists reduced the activation of microglia and astrocytes [153, 168,169,170,171]
Moreover the implications for diabetic stability and obesity management are not trivial if the medication is ceased
Novak M, Monkus EF, Buch M, and et al
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