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Clinical data from the SURMOUNT-1 trial published in the New England Journal of Medicine demonstrated dose-dependent weight loss: 16% average body weight reduction at 5mg, 21.4% at 10mg, and 22.5% at 15mg over 72 weeks
The venn diagram showed the number of Amplicon Sequence Variants (ASVs) of gut microbiota in the five groups of mice (Figure 5A)
The medication is expected to be a blockbuster for weight loss
Regular follow-up appointments should include monitoring of hemoglobin A1c, kidney function, and assessment for diabetic complications including neuropathy
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