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Finally, a discussion emerged regarding a specific population that may significantly benefit from combined therapy: individuals with obesity and T2D and high or very high cardiovascular risk or obesity
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Theoretically, GLP-1RAs can worsen liver fibrosis by stimulating M2 cell differentiation
Safety data indicate no major excess risk with combination therapy, although gastrointestinal effects and class-specific adverse events remain relevant
These different binding partners determine the names of the resultant vitamin B12 forms
