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At very high oral doses (54 mg), gastrointestinal side effects increased significantly
In vitro work by Sikiric and collaborators shows BPC-157 upregulates VEGFR2 expression in endothelial cells, which stimulates angiogenesis, the growth of new blood vessels into healing tissue
The peptide influences circadian rhythm regulation, making it valuable for travelers crossing time zones or night-shift workers trying to sleep during the day
PubMed Chang CH, et al
Latvia Studies in chicken embryos suggest that BPC 157 stimulates vascular development by activating VEGFR2, a cell surface receptor involved in nitric oxide signalling
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