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A few other side effects as well
Strategies that deplete GSH, such as using inhibitors like BSO which is inhibitor of -glutamylcysteine synthetase (-GCS) , the rate-limiting enzyme in glutathione (GSH) synthesis or by combining prodrug activation with GSH depletion in nanosystems, have shown promise in overcoming MDR and improving chemotherapy effectiveness [72]
268 , L699L722 (1995)
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There were also no significant changes in the slowness criteria measure using gait speed between the L-carnitine and placebo groups
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