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13 Both endogenously secreted GLP-1 and GIP are quickly cleared following release due to both renal clearance and rapid metabolism by the enzyme DPP-4

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Analysis of tumor PD-L1 expression and biomarkers in relation to clinical activity in patients (pts) with deficient DNA mismatch repair (dMMR)/high microsatellite instability (MSI-H) metastatic colorectal cancer (mCRC) treated with nivolumab (NIVO) 1 ipilimumab (IPI): CheckMate 142