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PlexusDx adds optional genetic context through the Precision Peptide Genetic Test to support discussion of individual peptide receptor sensitivity

11,23 The critical solution to the puzzle is the association between the discovered genes and ACPA production

WADA Prohibition The World Anti-Doping Agency classification for these peptides: GLP3 likely classified under prohibited substances as a GLP-1 receptor agonist Cagrilintide status as amylin analog may fall under peptide hormone prohibitions Combined formulation would be prohibited under multiple substance categories No Therapeutic Use Exemptions (TUEs) available for either component Detection methods under development for anti-doping testing WADAs position reflects that these remain investigational agents without regulatory approval from health authorities worldwide

Acknowledgements The authors express their gratitude to Maida Lekovic, Nerkeza Drekovic, and Nithad Granica for their technical support throughout the experiment, as well as to assistant professor Kimeta Hamidovic for proofreading the manuscript in English