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4.4 PIC micelles PIC micelles are delivery systems utilizing block copolymers, consisting of a neutral hydrophilic block and a cationic block, capable of responding to alterations in the biological environment such as pH, redox conditions, temperature, and salt concentration (109)
For instance, a protein may exhibit a single band in SDS-polyacrylamide gel electrophoresis (SDS-PAGE) but present three bands in isoelectric focusing
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Always label reconstituted vials with final concentration (mg/ml) and calculate injection volumes using a dosing table verified before the first administration
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