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GU, SM, FGconceptual guidance, critical revision and editing of the manuscript

To facilitate the CEA, the NNT measures were only estimated for the statistically significant clinical outcomes between study groups: all-cause death (HR [95% CI]: 0.40 [0.18, 0.91]) and hospitalized hypoglycemia (0.43 [0.27, 0.69])

Higher body weight can also make some MS symptoms more severe

As evidence accumulates, future studies may show greater long-term returns, potentially tipping the balance toward cost-effectiveness

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